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Therapeutic Targeting of DNA Replication Stress in Cancer
This article reviews the currently used therapeutic strategies to target DNA replication stress for cancer treatment in the clinic, highlighting their effectiveness and limitations due to toxicity and drug resistance. Cancer cells experience enhanced spontaneous DNA damage due to compromised DNA rep...
Autores principales: | Gu, Long, Hickey, Robert J., Malkas, Linda H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378776/ https://www.ncbi.nlm.nih.gov/pubmed/37510250 http://dx.doi.org/10.3390/genes14071346 |
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