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The Role of SOX9 in IGF-II-Mediated Pulmonary Fibrosis

Pulmonary fibrosis (PF) associated with systemic sclerosis (SSc) results in significant morbidity and mortality. We previously reported that insulin-like growth factor-II (IGF-II) is overexpressed in lung tissues and fibroblasts from SSc patients, and IGF-II fosters fibrosis by upregulating collagen...

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Detalles Bibliográficos
Autores principales: Waldrep, Kristy M., Rodgers, Jessalyn I., Garrett, Sara M., Wolf, Bethany J., Feghali-Bostwick, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378869/
https://www.ncbi.nlm.nih.gov/pubmed/37510994
http://dx.doi.org/10.3390/ijms241411234