Short Peptides of Innate Immunity Protein Tag7 (PGLYRP1) Selectively Induce Inhibition or Activation of Tumor Cell Death via TNF Receptor

In this study, we have found two peptides of Tag7 (PGLYRP1) protein-17.1A (HRDVQRT) and 17.1B (RSNYVLKG), that have different affinities to the TNFR1 receptor and the Hsp70 protein. Peptide 17.1A is able to inhibit signal transduction through the TNFR1 receptor, and peptide 17.1B can activate this r...

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Detalles Bibliográficos
Autores principales: Yurkina, Daria M., Sharapova, Tatiana N., Romanova, Elena A., Yashin, Denis V., Sashchenko, Lidia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379010/
https://www.ncbi.nlm.nih.gov/pubmed/37511122
http://dx.doi.org/10.3390/ijms241411363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379010/
https://www.ncbi.nlm.nih.gov/pubmed/37511122
http://dx.doi.org/10.3390/ijms241411363

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