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Drosophila as Model System to Study Ras-Mediated Oncogenesis: The Case of the Tensin Family of Proteins

Oncogenic mutations in the small GTPase Ras contribute to ~30% of human cancers. However, tissue growth induced by oncogenic Ras is restrained by the induction of cellular senescence, and additional mutations are required to induce tumor progression. Therefore, identifying cooperating cancer genes i...

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Detalles Bibliográficos
Autores principales: Martínez-Abarca Millán, Ana, Soler Beatty, Jennifer, Valencia Expósito, Andrea, Martín-Bermudo, María D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379045/
https://www.ncbi.nlm.nih.gov/pubmed/37510408
http://dx.doi.org/10.3390/genes14071502