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ERCC1 and MGMT Methylation as a Predictive Marker of Relapse and FOLFOX Response in Colorectal Cancer Patients from South Tunisia

Genetic and epigenetic modifications present a major cause of relapse and treatment failure in colorectal cancer. This study aims to appreciate the prognostic and predictive value of ERRC1 and MGMT methylation. We also studied the prognostic impact of the ERCC1 rs11615 polymorphism as well as its ex...

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Detalles Bibliográficos
Autores principales: Jamai, Dhouha, Gargouri, Raja, Selmi, Boulbaba, Khabir, Abdelmajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379058/
https://www.ncbi.nlm.nih.gov/pubmed/37510370
http://dx.doi.org/10.3390/genes14071467