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Using a Dual CRISPR/Cas9 Approach to Gain Insight into the Role of LRP1B in Glioblastoma

LRP1B remains one of the most altered genes in cancer, although its relevance in cancer biology is still unclear. Recent advances in gene editing techniques, particularly CRISPR/Cas9 systems, offer new opportunities to evaluate the function of large genes, such as LRP1B. Using a dual sgRNA CRISPR/Ca...

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Detalles Bibliográficos
Autores principales: Peixoto, Joana, Príncipe, Catarina, Pestana, Ana, Osório, Hugo, Pinto, Marta Teixeira, Prazeres, Hugo, Soares, Paula, Lima, Raquel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379115/
https://www.ncbi.nlm.nih.gov/pubmed/37511044
http://dx.doi.org/10.3390/ijms241411285