Hyperuricaemia Does Not Interfere with Aortopathy in a Murine Model of Marfan Syndrome

Redox stress is involved in the aortic aneurysm pathogenesis in Marfan syndrome (MFS). We recently reported that allopurinol, a xanthine oxidoreductase inhibitor, blocked aortopathy in a MFS mouse model acting as an antioxidant without altering uric acid (UA) plasma levels. Hyperuricaemia is ambiguo...

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Detalles Bibliográficos
Autores principales: Rodríguez-Rovira, Isaac, López-Sainz, Angela, Palomo-Buitrago, Maria Encarnación, Pérez, Belen, Jiménez-Altayó, Francesc, Campuzano, Victoria, Egea, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379183/
https://www.ncbi.nlm.nih.gov/pubmed/37511051
http://dx.doi.org/10.3390/ijms241411293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379183/
https://www.ncbi.nlm.nih.gov/pubmed/37511051
http://dx.doi.org/10.3390/ijms241411293

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