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Hyperuricaemia Does Not Interfere with Aortopathy in a Murine Model of Marfan Syndrome

Redox stress is involved in the aortic aneurysm pathogenesis in Marfan syndrome (MFS). We recently reported that allopurinol, a xanthine oxidoreductase inhibitor, blocked aortopathy in a MFS mouse model acting as an antioxidant without altering uric acid (UA) plasma levels. Hyperuricaemia is ambiguo...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Rovira, Isaac, López-Sainz, Angela, Palomo-Buitrago, Maria Encarnación, Pérez, Belen, Jiménez-Altayó, Francesc, Campuzano, Victoria, Egea, Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379183/ https://www.ncbi.nlm.nih.gov/pubmed/37511051 http://dx.doi.org/10.3390/ijms241411293

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