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Epigenomics Analysis of the Suppression Role of SIRT1 via H3K9 Deacetylation in Preadipocyte Differentiation

Sirtuin 1 (SIRT1) overexpression significantly inhibits lipid deposition during yak intramuscular preadipocyte (YIMA) differentiation; however, the regulatory mechanism remains unknown. We elucidated the role of SIRT1 in YIMA differentiation using lentivirus-mediated downregulation technology and co...

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Detalles Bibliográficos
Autores principales: Yang, Youzhualamu, Peng, Wei, Su, Xiaolong, Yue, Binglin, Shu, Shi, Wang, Jikun, Fu, Changqi, Zhong, Jincheng, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379189/
https://www.ncbi.nlm.nih.gov/pubmed/37511041
http://dx.doi.org/10.3390/ijms241411281