SF3B1 Mutations Are Associated with Resistance to Non-Genotoxic MDM2 Inhibition in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is a genetically and clinically heterogeneous malignancy affecting older individuals. There are a number of current treatment options for CLL, including monoclonal antibodies, targeted drugs, chemotherapy, and different combinations of these. However, for those pat...

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Detalles Bibliográficos
Autores principales: Aptullahoglu, Erhan, Wallis, Jonathan P., Marr, Helen, Marshall, Scott, Bown, Nick, Willmore, Elaine, Lunec, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379212/
https://www.ncbi.nlm.nih.gov/pubmed/37511096
http://dx.doi.org/10.3390/ijms241411335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379212/
https://www.ncbi.nlm.nih.gov/pubmed/37511096
http://dx.doi.org/10.3390/ijms241411335

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