Is It Possible to Obtain a Product of the Desired Configuration from a Single Knoevenagel Condensation? Isomerization vs. Stereodefined Synthesis

The biological activity of compounds directly depends on the three-dimensional arrangement of affinity fragments since a high degree of pharmacophore compliance with the binding site is required. 3-Benzylidene oxindoles are privileged structures due to their wide spectrum of biological activity, syn...

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Detalles Bibliográficos
Autores principales: Novikova, Daria, Grigoreva, Tatyana, Gurzhiy, Vladislav, Tribulovich, Vyacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379276/
https://www.ncbi.nlm.nih.gov/pubmed/37511099
http://dx.doi.org/10.3390/ijms241411339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379276/
https://www.ncbi.nlm.nih.gov/pubmed/37511099
http://dx.doi.org/10.3390/ijms241411339

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