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Targeting SOX18 Transcription Factor Activity by Small-Molecule Inhibitor Sm4 in Non-Small Lung Cancer Cell Lines

The transcription factor SOX18 has been shown to play a crucial role in lung cancer progression and metastasis. In this study, we investigated the effect of Sm4, a SOX18 inhibitor, on cell cycle regulation in non-small cell lung cancer (NSCLC) cell lines LXF-289 and SK-MES-1, as well as normal human...

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Detalles Bibliográficos
Autores principales: Rodak, Olga, Mrozowska, Monika, Rusak, Agnieszka, Gomułkiewicz, Agnieszka, Piotrowska, Aleksandra, Olbromski, Mateusz, Podhorska-Okołów, Marzenna, Ugorski, Maciej, Dzięgiel, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379584/
https://www.ncbi.nlm.nih.gov/pubmed/37511076
http://dx.doi.org/10.3390/ijms241411316