Cognitive Normal Older Adults with APOE-2 Allele Show a Distinctive Functional Connectivity Pattern in Response to Cerebral Aβ Deposition

The ε2 allele of apolipoprotein E (ε2) has neuroprotective effects against beta-amyloid (Aβ) pathology in Alzheimer’s disease (AD). However, its impact on the functional connectivity and hub efficiency in cognitively normal older adults (CN) with ε2 is unclear. We investigated the functional connect...

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Detalles Bibliográficos
Autores principales: Wang, Sheng-Min, Kang, Dong Woo, Um, Yoo Hyun, Kim, Sunghwan, Kim, Regina E. Y., Kim, Donghyeon, Lee, Chang Uk, Lim, Hyun Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380008/
https://www.ncbi.nlm.nih.gov/pubmed/37511008
http://dx.doi.org/10.3390/ijms241411250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380008/
https://www.ncbi.nlm.nih.gov/pubmed/37511008
http://dx.doi.org/10.3390/ijms241411250

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