Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates

Prostate cancer is the second most common cancer among men. We designed and synthesized new ligands targeting prostate-specific membrane antigen and suitable for bimodal conjugates with diagnostic and therapeutic agents. In vitro studies of the affinity of the synthesized compounds to the protein ta...

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Detalles Bibliográficos
Autores principales: Zyk, Nikolai Y., Garanina, Anastasiia S., Plotnikova, Ekaterina A., Ber, Anton P., Nimenko, Ekaterina A., Dashkova, Natalia S., Uspenskaia, Anastasiia A., Shafikov, Radik R., Skvortsov, Dmitry A., Petrov, Stanislav A., Pankratov, Andrey A., Zyk, Nikolai V., Majouga, Alexander G., Beloglazkina, Elena K., Machulkin, Aleksei E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380083/
https://www.ncbi.nlm.nih.gov/pubmed/37511087
http://dx.doi.org/10.3390/ijms241411327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380083/
https://www.ncbi.nlm.nih.gov/pubmed/37511087
http://dx.doi.org/10.3390/ijms241411327

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