Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization

Immune responses in humanized mice are generally inefficient without co-transplantation of human thymus or HLA transgenes. Previously, we generated humanized mice via the intra-bone marrow injection of CD133+ cord blood cells into irradiated adult immunodeficient mice (IBMI-huNSG mice), which could...

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Detalles Bibliográficos
Autores principales: Fukuhara, Takataro, Ueda, Yoshihiro, Lee, Sung-Il, Odaka, Tokifumi, Nakajima, Shinsuke, Fujisawa, Jun-Ichi, Okuma, Kazu, Naganuma, Makoto, Okazaki, Kazuichi, Kondo, Naoyuki, Kamioka, Yuji, Matsumoto, Mitsuru, Kinashi, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380196/
https://www.ncbi.nlm.nih.gov/pubmed/37511462
http://dx.doi.org/10.3390/ijms241411705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380196/
https://www.ncbi.nlm.nih.gov/pubmed/37511462
http://dx.doi.org/10.3390/ijms241411705

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