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Thymocyte Development of Humanized Mice Is Promoted by Interactions with Human-Derived Antigen Presenting Cells upon Immunization

Immune responses in humanized mice are generally inefficient without co-transplantation of human thymus or HLA transgenes. Previously, we generated humanized mice via the intra-bone marrow injection of CD133+ cord blood cells into irradiated adult immunodeficient mice (IBMI-huNSG mice), which could...

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Detalles Bibliográficos
Autores principales:	Fukuhara, Takataro, Ueda, Yoshihiro, Lee, Sung-Il, Odaka, Tokifumi, Nakajima, Shinsuke, Fujisawa, Jun-Ichi, Okuma, Kazu, Naganuma, Makoto, Okazaki, Kazuichi, Kondo, Naoyuki, Kamioka, Yuji, Matsumoto, Mitsuru, Kinashi, Tatsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380196/ https://www.ncbi.nlm.nih.gov/pubmed/37511462 http://dx.doi.org/10.3390/ijms241411705

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