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TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of Colorectal Carcinoma

Colorectal carcinoma (CRC) is a prevalent cancer worldwide with a high mortality rate. Evidence suggests that increased expression of Cyclin-dependent kinase 5 (CDK5) contributes to cancer progression, making it a promising target for treatment. This study examined the efficacy of selectively inhibi...

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Detalles Bibliográficos
Autores principales: Amin, Niranjana, Wang, Herui, Song, Qi, Bhaskar, Manju, Yadav, Sharda Prasad, Gilbert, Mark R., Pant, Harish, Tabouret, Emeline, Zhuang, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380212/
https://www.ncbi.nlm.nih.gov/pubmed/37511490
http://dx.doi.org/10.3390/ijms241411733