Spatially Resolved Proteomic and Transcriptomic Profiling of Anaplastic Lymphoma Kinase-Rearranged Pulmonary Adenocarcinomas Reveals Key Players in Inter- and Intratumoral Heterogeneity

Pulmonary adenocarcinomas (pADCs) with an ALK rearrangement are a rare cancer subtype, necessitating comprehensive molecular investigations to unravel their heterogeneity and improve therapeutic strategies. In this pilot study, we employed spatial transcriptomic (NanoString GeoMx) and proteomic prof...

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Detalles Bibliográficos
Autores principales: Szeitz, Beáta, Glasz, Tibor, Herold, Zoltán, Tóth, Gábor, Balbisi, Mirjam, Fillinger, János, Horváth, Szabolcs, Mohácsi, Réka, Kwon, Ho Jeong, Moldvay, Judit, Turiák, Lilla, Szász, Attila Marcell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380216/
https://www.ncbi.nlm.nih.gov/pubmed/37511126
http://dx.doi.org/10.3390/ijms241411369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380216/
https://www.ncbi.nlm.nih.gov/pubmed/37511126
http://dx.doi.org/10.3390/ijms241411369

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