A FRET-Based Assay for the Identification of PCNA Inhibitors

Proliferating cell nuclear antigen (PCNA) is the key regulator of human DNA metabolism. One important interaction partner is p15, involved in DNA replication and repair. Targeting the PCNA–p15 interaction is a promising therapeutic strategy against cancer. Here, a Förster resonance energy transfer (...

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Detalles Bibliográficos
Autores principales: Hardebeck, Sarah, Schreiber, Sebastian, Adick, Annika, Langer, Klaus, Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380293/
https://www.ncbi.nlm.nih.gov/pubmed/37511614
http://dx.doi.org/10.3390/ijms241411858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380293/
https://www.ncbi.nlm.nih.gov/pubmed/37511614
http://dx.doi.org/10.3390/ijms241411858

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