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Suppression of NASH-Related HCC by Farnesyltransferase Inhibitor through Inhibition of Inflammation and Hypoxia-Inducible Factor-1α Expression

Inflammatory processes play major roles in carcinogenesis and the progression of hepatocellular carcinoma (HCC) derived from non-alcoholic steatohepatitis (NASH). But, there are no therapies for NASH-related HCC, especially focusing on these critical steps. Previous studies have reported that farnes...

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Detalles Bibliográficos
Autores principales: Yamada, Kohei, Tanaka, Tomokazu, Kai, Keita, Matsufuji, Shohei, Ito, Kotaro, Kitajima, Yoshihiko, Manabe, Tatsuya, Noshiro, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380354/
https://www.ncbi.nlm.nih.gov/pubmed/37511305
http://dx.doi.org/10.3390/ijms241411546