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Chimerism Testing by Next Generation Sequencing for Detection of Engraftment and Early Disease Relapse in Allogeneic Hematopoietic Cell Transplantation and an Overview of NGS Chimerism Studies

Chimerism monitoring after allogenic Hematopoietic Cell Transplantation (allo-HCT) is critical to determine how well donor cells have engrafted and to detect relapse for early therapeutic intervention. The aim of this study was to establish and detect mixed chimerism and minimal residual disease usi...

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Detalles Bibliográficos
Autores principales: Liacini, Abdelhamid, Tripathi, Gaurav, McCollick, Amanda, Gravante, Christopher, Abdelmessieh, Peter, Shestovska, Yuliya, Mathew, Leena, Geier, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380370/
https://www.ncbi.nlm.nih.gov/pubmed/37511573
http://dx.doi.org/10.3390/ijms241411814