Esaxerenone Inhibits Renal Angiogenesis and Endothelial-Mesenchymal Transition via the VEGFA and TGF-β1 Pathways in Aldosterone-Infused Mice

Renal fibrosis is an inevitable process in the progression of chronic kidney disease (CKD). Angiogenesis plays an important role in this process. Vascular endothelial cells are involved in renal fibrosis by phenotypic transformation and secretion of extracellular matrix. Aldosterone stimulates miner...

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Detalles Bibliográficos
Autores principales: Gao, Xiaomeng, Chang, Jingyue, Chang, Yi, Fan, Lili, Liu, Ziqian, Zhang, Cuijuan, Shimosawa, Tatsuo, Yang, Fan, Xu, Qingyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380380/
https://www.ncbi.nlm.nih.gov/pubmed/37511521
http://dx.doi.org/10.3390/ijms241411766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380380/
https://www.ncbi.nlm.nih.gov/pubmed/37511521
http://dx.doi.org/10.3390/ijms241411766

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