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Esaxerenone Inhibits Renal Angiogenesis and Endothelial-Mesenchymal Transition via the VEGFA and TGF-β1 Pathways in Aldosterone-Infused Mice
Renal fibrosis is an inevitable process in the progression of chronic kidney disease (CKD). Angiogenesis plays an important role in this process. Vascular endothelial cells are involved in renal fibrosis by phenotypic transformation and secretion of extracellular matrix. Aldosterone stimulates miner...
Autores principales: | Gao, Xiaomeng, Chang, Jingyue, Chang, Yi, Fan, Lili, Liu, Ziqian, Zhang, Cuijuan, Shimosawa, Tatsuo, Yang, Fan, Xu, Qingyou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380380/ https://www.ncbi.nlm.nih.gov/pubmed/37511521 http://dx.doi.org/10.3390/ijms241411766 |
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