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Staphylococcal Enterotoxin C2 Mutant-Induced Antitumor Immune Response Is Controlled by CDC42/MLC2-Mediated Tumor Cell Stiffness

As a biological macromolecule, the superantigen staphylococcal enterotoxin C2 (SEC2) is one of the most potent known T-cell activators, and it induces massive cytotoxic granule production. With this property, SEC2 and its mutants are widely regarded as immunomodulating agents for cancer therapy. In...

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Detalles Bibliográficos
Autores principales: Fu, Xuanhe, Xu, Mingkai, Yu, Zhixiong, Gu, Wu, Zhang, Zhichun, Zhang, Bowen, Wang, Xiujuan, Su, Zhencheng, Zhang, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380429/
https://www.ncbi.nlm.nih.gov/pubmed/37511553
http://dx.doi.org/10.3390/ijms241411796