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Intraperitoneal Injection of Human Ferritin Heavy Chain Attenuates the Atherosclerotic Process in APOE-Knockout Mice

Background: Iron overload can accelerate the accumulation of lipid oxides and contribute to the progression of atherosclerosis. Ferritin heavy chain (FT-H) exhibits oxidase activity, which inhibits the toxicity of ferrous ions and reduces oxidative damage. We investigated the effect of the intraperi...

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Detalles Bibliográficos
Autores principales: Yuan, Wanzhong, Zhang, Jianlin, Huo, Ran, Hou, Chaofan, Yang, Jun, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380433/
https://www.ncbi.nlm.nih.gov/pubmed/37504565
http://dx.doi.org/10.3390/jcdd10070309