Intranasally Administered MSC-Derived Extracellular Vesicles Reverse Cisplatin-Induced Cognitive Impairment

Neurotoxic side effects of chemotherapy include deficits in attention, memory, and executive functioning. Currently, there are no FDA-approved therapies. In mice, cisplatin causes long-term cognitive deficits, white matter damage, mitochondrial dysfunction, and loss of synaptic integrity. We hypothe...

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Detalles Bibliográficos
Autores principales: Milutinovic, Bojana, Mahalingam, Rajasekaran, Mendt, Mayela, Arroyo, Luis, Seua, Alexandre, Dharmaraj, Shruti, Shpall, Elizabeth, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380450/
https://www.ncbi.nlm.nih.gov/pubmed/37511623
http://dx.doi.org/10.3390/ijms241411862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380450/
https://www.ncbi.nlm.nih.gov/pubmed/37511623
http://dx.doi.org/10.3390/ijms241411862

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