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Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia

When stimulated by proinflammatory mediators, endothelial cells release ultra-large von Willebrand factor (ULVWF) multimers that are hyperactive in activating and aggregating platelets. These ULVWF multimers can accumulate in the circulation and on the inflamed endothelium because they are insuffici...

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Detalles Bibliográficos
Autores principales: Gao, Daniel, Zhou, Zhou, Ma, Ruidong, Wu, Huaizhu, Nguyen, Trung, Liu, Li, Dong, Jingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380474/
https://www.ncbi.nlm.nih.gov/pubmed/37511541
http://dx.doi.org/10.3390/ijms241411782