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Recombinant ADAMTS-13 Improves Survival of Mice Subjected to Endotoxemia
When stimulated by proinflammatory mediators, endothelial cells release ultra-large von Willebrand factor (ULVWF) multimers that are hyperactive in activating and aggregating platelets. These ULVWF multimers can accumulate in the circulation and on the inflamed endothelium because they are insuffici...
Autores principales: | Gao, Daniel, Zhou, Zhou, Ma, Ruidong, Wu, Huaizhu, Nguyen, Trung, Liu, Li, Dong, Jingfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380474/ https://www.ncbi.nlm.nih.gov/pubmed/37511541 http://dx.doi.org/10.3390/ijms241411782 |
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