Exploring the Potential of a Genome-Reduced Escherichia coli Strain for Plasmid DNA Production

The global demand for nucleic acid-based vaccines, including plasmid DNA (pDNA) and mRNA vaccines, needs efficient production platforms. However, conventional hosts for plasmid production have encountered challenges related to sequence integrity due to the presence of insertion sequences (ISs). In t...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Thuy, Bui, Le Minh, Byun, Ji-Young, Cho, Byung-Kwan, Kim, Sun Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380479/
https://www.ncbi.nlm.nih.gov/pubmed/37511505
http://dx.doi.org/10.3390/ijms241411749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380479/
https://www.ncbi.nlm.nih.gov/pubmed/37511505
http://dx.doi.org/10.3390/ijms241411749

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