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α5-GABAA Receptor Modulation Reverses Behavioral and Neurophysiological Correlates of Psychosis in Rats with Ventral Hippocampal Alzheimer’s Disease-like Pathology

Of the 35 million people in the world suffering from Alzheimer’s Disease (AD), up to half experience comorbid psychosis. Antipsychotics, used to treat psychosis, are contraindicated in elderly patients because they increase the risk of premature death. Reports indicate that the hippocampus is hypera...

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Detalles Bibliográficos
Autores principales: Eassa, Nicole E., Perez, Stephanie M., Boley, Angela M., Elam, Hannah B., Sharmin, Dishary, Cook, James M., Lodge, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380527/
https://www.ncbi.nlm.nih.gov/pubmed/37511546
http://dx.doi.org/10.3390/ijms241411788