The UPR Maintains Proteostasis and the Viability and Function of Hippocampal Neurons in Adult Mice

The unfolded protein response (UPR), which comprises three branches: PERK, ATF6α, and IRE1, is a major mechanism for maintaining cellular proteostasis. Many studies show that the UPR is a major player in regulating neuron viability and function in various neurodegenerative diseases; however, its rol...

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Detalles Bibliográficos
Autores principales: Liu, Pingting, Karim, Md Razaul, Covelo, Ana, Yue, Yuan, Lee, Michael K., Lin, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380539/
https://www.ncbi.nlm.nih.gov/pubmed/37511300
http://dx.doi.org/10.3390/ijms241411542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380539/
https://www.ncbi.nlm.nih.gov/pubmed/37511300
http://dx.doi.org/10.3390/ijms241411542

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