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The UPR Maintains Proteostasis and the Viability and Function of Hippocampal Neurons in Adult Mice
The unfolded protein response (UPR), which comprises three branches: PERK, ATF6α, and IRE1, is a major mechanism for maintaining cellular proteostasis. Many studies show that the UPR is a major player in regulating neuron viability and function in various neurodegenerative diseases; however, its rol...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380539/ https://www.ncbi.nlm.nih.gov/pubmed/37511300 http://dx.doi.org/10.3390/ijms241411542 |