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Role of Mouse Organic Cation Transporter 2 for Nephro- and Peripheral Neurotoxicity Induced by Chemotherapeutic Treatment with Cisplatin

Cisplatin (CDDP) is an efficient chemotherapeutic agent broadly used to treat solid cancers. Chemotherapy with CDDP can cause significant unwanted side effects such as renal toxicity and peripheral neurotoxicity. CDDP is a substrate of organic cation transporters (OCT), transporters that are highly...

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Detalles Bibliográficos
Autores principales: Hucke, Anna, Schröter, Rita, Ceresa, Cecilia, Chiorazzi, Alessia, Canta, Annalisa, Semperboni, Sara, Marmiroli, Paola, Cavaletti, Guido, Gess, Burkhard, Ciarimboli, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380567/
https://www.ncbi.nlm.nih.gov/pubmed/37511245
http://dx.doi.org/10.3390/ijms241411486