PDE4 Inhibitors: Profiling Hits through the Multitude of Structural Classes

Cyclic nucleotide phosphodiesterases 4 (PDE4) are a family of enzymes which specifically promote the hydrolysis and degradation of cAMP. The inhibition of PDE4 enzymes has been widely investigated as a possible alternative strategy for the treatment of a variety of respiratory diseases, including ch...

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Detalles Bibliográficos
Autores principales: Jin, Jian, Mazzacuva, Francesca, Crocetti, Letizia, Giovannoni, Maria Paola, Cilibrizzi, Agostino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380597/
https://www.ncbi.nlm.nih.gov/pubmed/37511275
http://dx.doi.org/10.3390/ijms241411518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380597/
https://www.ncbi.nlm.nih.gov/pubmed/37511275
http://dx.doi.org/10.3390/ijms241411518

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