Downregulation of PACAP and the PAC1 Receptor in the Basal Ganglia, Substantia Nigra and Centrally Projecting Edinger–Westphal Nucleus in the Rotenone model of Parkinson’s Disease

Numerous in vitro and in vivo models of Parkinson’s disease (PD) demonstrate that pituitary adenylate cyclase-activating polypeptide (PACAP) conveys its strong neuroprotective actions mainly via its specific PAC1 receptor (PAC1R) in models of PD. We recently described the decrease in PAC1R protein c...

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Detalles Bibliográficos
Autores principales: Fehér, Máté, Márton, Zsombor, Szabó, Ákos, Kocsa, János, Kormos, Viktória, Hunyady, Ágnes, Kovács, László Ákos, Ujvári, Balázs, Berta, Gergely, Farkas, József, Füredi, Nóra, Gaszner, Tamás, Pytel, Bence, Reglődi, Dóra, Gaszner, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380602/
https://www.ncbi.nlm.nih.gov/pubmed/37511603
http://dx.doi.org/10.3390/ijms241411843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380602/
https://www.ncbi.nlm.nih.gov/pubmed/37511603
http://dx.doi.org/10.3390/ijms241411843

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