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Loss of ANCO1 Expression Regulates Chromatin Accessibility and Drives Progression of Early-Stage Triple-Negative Breast Cancer

Mutations in the gene ankyrin repeat domain containing 11 (ANKRD11/ANCO1) play a role in neurodegenerative disorders, and its loss of heterozygosity and low expression are seen in some cancers. Here, we show that low ANCO1 mRNA and protein expression levels are prognostic markers for poor clinical o...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Barefoot, Megan E., Peterson, Kendell, Campbell, Moray J., Blancato, Jan K., Chen, Manjing, Schmidt, Marcel O., Kiliti, Amber J., Fang, Hong-Bin, Wellstein, Anton, Riegel, Anna T., Sharif, Ghada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380654/
https://www.ncbi.nlm.nih.gov/pubmed/37511268
http://dx.doi.org/10.3390/ijms241411505