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Induced Heteroresistance in Carbapenem-Resistant Acinetobacter baumannii (CRAB) via Exposure to Human Pleural Fluid (HPF) and Its Impact on Cefiderocol Susceptibility

Infections caused by Carbapenem-resistant Acinetobacter baumannii (CRAB) isolates, such as hospital-acquired pneumonia (HAP), bacteremia, and skin and soft tissue infections, among others, are particularly challenging to treat. Cefiderocol, a chlorocatechol-substituted siderophore antibiotic, was ap...

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Detalles Bibliográficos
Autores principales: Mezcord, Vyanka, Escalante, Jenny, Nishimura, Brent, Traglia, German M., Sharma, Rajnikant, Vallé, Quentin, Tuttobene, Marisel R., Subils, Tomás, Marin, Ingrid, Pasteran, Fernando, Actis, Luis A., Tolmasky, Marcelo E., Bonomo, Robert A., Rao, Gauri, Ramirez, María S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380697/
https://www.ncbi.nlm.nih.gov/pubmed/37511511
http://dx.doi.org/10.3390/ijms241411752