Low Expression of the NRP1 Gene Is Associated with Shorter Overall Survival in Patients with Sonic Hedgehog and Group 3 Medulloblastoma

Medulloblastoma (MB) is the most common type of malignant pediatric brain tumor. Neuropilin-1 (NRP1), encoded by the NRP1 gene, is a transmembrane glycoprotein overexpressed in several types of cancer. Previous studies indicate that NRP1 inhibition displays antitumor effects in MB models and higher...

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Detalles Bibliográficos
Autores principales: de Araújo, Moisés Augusto, Malafaia, Osvaldo, Ribas Filho, Jurandir M., Fratini, Livia, Roesler, Rafael, Isolan, Gustavo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380701/
https://www.ncbi.nlm.nih.gov/pubmed/37511358
http://dx.doi.org/10.3390/ijms241411601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380701/
https://www.ncbi.nlm.nih.gov/pubmed/37511358
http://dx.doi.org/10.3390/ijms241411601

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