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Multiple Roles of LOXL2 in the Progression of Hepatocellular Carcinoma and Its Potential for Therapeutic Targeting

LOXL2, a copper-dependent amine oxidase, has emerged as a promising therapeutic target in hepatocellular carcinoma (HCC). Increased LOXL2 expression in HCC has been linked with an aggressive phenotype and represents a poor prognostic factor. Here, we focus on the mechanisms through which LOXL2 orche...

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Detalles Bibliográficos
Autores principales: Radić, Jelena, Kožik, Bojana, Nikolić, Ivan, Kolarov-Bjelobrk, Ivana, Vasiljević, Tijana, Vranjković, Bojana, Despotović, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380739/
https://www.ncbi.nlm.nih.gov/pubmed/37511503
http://dx.doi.org/10.3390/ijms241411745