Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells

Heat shock protein 70 (HSP70) regulates the ligand binding of the glucocorticoid receptor (GR). In asthma patients, heat treatment increased both the GR expression and secretion of extracellular HSP70 (eHSP70) by bronchial epithelial cells (EC). The objective of this study was to assess the effects...

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Detalles Bibliográficos
Autores principales: Zhou, Liang, Fang, Lei, Tamm, Michael, Stolz, Daiana, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380817/
https://www.ncbi.nlm.nih.gov/pubmed/37511459
http://dx.doi.org/10.3390/ijms241411700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380817/
https://www.ncbi.nlm.nih.gov/pubmed/37511459
http://dx.doi.org/10.3390/ijms241411700

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