Impaired Insulin Signaling Mediated by the Small GTPase Rac1 in Skeletal Muscle of the Leptin-Deficient Obese Mouse

Insulin-stimulated glucose uptake in skeletal muscle is mediated by the glucose transporter GLUT4. The small GTPase Rac1 acts as a switch of signal transduction that regulates GLUT4 translocation to the plasma membrane following insulin stimulation. However, it remains obscure whether signaling casc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Man Piu, Takenaka, Nobuyuki, Satoh, Takaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380855/
https://www.ncbi.nlm.nih.gov/pubmed/37511290
http://dx.doi.org/10.3390/ijms241411531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380855/
https://www.ncbi.nlm.nih.gov/pubmed/37511290
http://dx.doi.org/10.3390/ijms241411531

Ejemplares similares