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T1AM/TAAR1 System Reduces Inflammatory Response and β-Amyloid Toxicity in Human Microglial HMC3 Cell Line

Microglial dysfunction is one of the hallmarks and leading causes of common neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD) and Parkinson’s disease (PD). All these pathologies are characterized by aberrant aggregation of disease-causing proteins in the brain, which can directly...

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Detalles Bibliográficos
Autores principales: Polini, Beatrice, Ricardi, Caterina, Bertolini, Andrea, Carnicelli, Vittoria, Rutigliano, Grazia, Saponaro, Federica, Zucchi, Riccardo, Chiellini, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380917/
https://www.ncbi.nlm.nih.gov/pubmed/37511328
http://dx.doi.org/10.3390/ijms241411569