Single Cell Transcriptomic Analysis in a Mouse Model of Barth Syndrome Reveals Cell-Specific Alterations in Gene Expression and Intercellular Communication

Barth Syndrome, a rare X-linked disorder affecting 1:300,000 live births, results from defects in Tafazzin, an acyltransferase that remodels cardiolipin and is essential for mitochondrial respiration. Barth Syndrome patients develop cardiomyopathy, muscular hypotonia and cyclic neutropenia during ch...

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Detalles Bibliográficos
Autores principales: Perera, Gayani, Power, Liam, Larson, Amy, Codden, Christina J., Awata, Junya, Batorsky, Rebecca, Strathdee, Douglas, Chin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380964/
https://www.ncbi.nlm.nih.gov/pubmed/37511352
http://dx.doi.org/10.3390/ijms241411594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380964/
https://www.ncbi.nlm.nih.gov/pubmed/37511352
http://dx.doi.org/10.3390/ijms241411594

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