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The Role of Genetics and Epigenetic Regulation in the Pathogenesis of Osteoarthritis
Osteoarthritis (OA) is progressive disease characterised by cartilage degradation, subchondral bone remodelling and inflammation of the synovium. The disease is associated with obesity, mechanical load and age. However, multiple pro-inflammatory immune mediators regulate the expression of metallopro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381003/ https://www.ncbi.nlm.nih.gov/pubmed/37511413 http://dx.doi.org/10.3390/ijms241411655 |