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The Role of Genetics and Epigenetic Regulation in the Pathogenesis of Osteoarthritis

Osteoarthritis (OA) is progressive disease characterised by cartilage degradation, subchondral bone remodelling and inflammation of the synovium. The disease is associated with obesity, mechanical load and age. However, multiple pro-inflammatory immune mediators regulate the expression of metallopro...

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Detalles Bibliográficos
Autores principales:	Kiełbowski, Kajetan, Herian, Mariola, Bakinowska, Estera, Banach, Bolesław, Sroczyński, Tomasz, Pawlik, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381003/ https://www.ncbi.nlm.nih.gov/pubmed/37511413 http://dx.doi.org/10.3390/ijms241411655

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