Sex-Specific Protection of Endothelial Function after Vascular Ischemia/Reperfusion Injury by the Senomorphic Agent Ruxolitinib

Ischemia/reperfusion (I/R)-induced endothelial dysfunction occurs in various cardiovascular disorders. I/R injury is partially driven by the release of cytokines. Known for its use in senotherapy, the JAK inhibitor ruxolitinib is able to block the release of cytokines. We investigated the effect of...

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Detalles Bibliográficos
Autores principales: Saemann, Lars, Naujoks, Paula, Hartrumpf, Lotta, Pohl, Sabine, Simm, Andreas, Szabó, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381013/
https://www.ncbi.nlm.nih.gov/pubmed/37511486
http://dx.doi.org/10.3390/ijms241411727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381013/
https://www.ncbi.nlm.nih.gov/pubmed/37511486
http://dx.doi.org/10.3390/ijms241411727

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