UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1

Premature telomere shortening is a known factor correlated to idiopathic pulmonary fibrosis (IPF) occurrence, which is a chronic, progressive, age-related disease with high mortality. The etiology of IPF is still unknown. Here, we found that UBQLN1 plays a key role in telomere length maintenance and...

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Detalles Bibliográficos
Autores principales: Zhou, Haoxian, Xie, Chen, Xie, Yujie, He, Yunru, Chen, Yanlian, Zhang, Canfeng, Zhang, Yan, Zhao, Yong, Liu, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381042/
https://www.ncbi.nlm.nih.gov/pubmed/37463174
http://dx.doi.org/10.1371/journal.pgen.1010856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381042/
https://www.ncbi.nlm.nih.gov/pubmed/37463174
http://dx.doi.org/10.1371/journal.pgen.1010856

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