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UBQLN1 deficiency mediates telomere shortening and IPF through interacting with RPA1
Premature telomere shortening is a known factor correlated to idiopathic pulmonary fibrosis (IPF) occurrence, which is a chronic, progressive, age-related disease with high mortality. The etiology of IPF is still unknown. Here, we found that UBQLN1 plays a key role in telomere length maintenance and...
Autores principales: | Zhou, Haoxian, Xie, Chen, Xie, Yujie, He, Yunru, Chen, Yanlian, Zhang, Canfeng, Zhang, Yan, Zhao, Yong, Liu, Haiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381042/ https://www.ncbi.nlm.nih.gov/pubmed/37463174 http://dx.doi.org/10.1371/journal.pgen.1010856 |
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