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A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled

Epithelial tissues can be polarized along two axes: in addition to apical-basal polarity they are often also polarized within the plane of the epithelium, known as planar cell polarity (PCP). PCP depends upon the conserved Wnt/Frizzled (Fz) signaling factors, including Fz itself and Van Gogh (Vang/V...

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Detalles Bibliográficos
Autores principales: Humphries, Ashley C., Molina-Pelayo, Claudia, Sil, Parijat, Hazelett, C. Clayton, Devenport, Danelle, Mlodzik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381084/
https://www.ncbi.nlm.nih.gov/pubmed/37463168
http://dx.doi.org/10.1371/journal.pgen.1010849