Mycobacterium avium subsp. paratuberculosis Antigens Elicit a Strong IgG4 Response in Patients with Multiple Sclerosis and Exacerbate Experimental Autoimmune Encephalomyelitis

Neuroinflammation can be triggered by microbial products disrupting immune regulation. In this study, we investigated the levels of IgG1, IgG2, IgG3, and IgG4 subclasses against the heat shock protein (HSP)70(533–545) peptide and lipopentapeptide (MAP_Lp5) derived from Mycobacterium avium subsp. par...

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Detalles Bibliográficos
Autores principales: Cossu, Davide, Tomizawa, Yuji, Yokoyama, Kazumasa, Sakanishi, Tamami, Momotani, Eiichi, Sechi, Leonardo A., Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381415/
https://www.ncbi.nlm.nih.gov/pubmed/37511812
http://dx.doi.org/10.3390/life13071437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381415/
https://www.ncbi.nlm.nih.gov/pubmed/37511812
http://dx.doi.org/10.3390/life13071437

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